FIRE-pro is a nice extension of FIRE to find protein motifs from large-scale proteomic datasets. Like FIRE, it is an unbiased, de novo motif discovery tool, which will discover motifs that best explain how proteins or peptides behave in your dataset. We showed in the paper that many of the motifs discovered by FIRE-pro match known motifs, e.g phosphorylation sites, localization and degradation signals.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0014444
Advertisement
